Biomolecules & Therapeutics 2022; 30(6): 479~624
Modulation of Reactive Oxygen Species to Overcome 5-Fluorouracil Resistance
Kyung-Soo Chun and Sang Hoon Joo
Biomolecules & Therapeutics 2022; 30(6): 479-489  
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Senotherapeutics and Their Molecular Mechanism for Improving Aging
Jooho Park and Dong Wook Shin
Biomolecules & Therapeutics 2022; 30(6): 490-500  
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Original Articles
p38 MAPK Inhibitor NJK14047 Suppresses CDNB-Induced Atopic Dermatitis-Like Symptoms in BALB/c Mice
Ju-Hyun Lee, Seung-Hwan Son, Nam-Jung Kim and Dong-Soon Im
Biomolecules & Therapeutics 2022; 30(6): 501-509  
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Effects of Dextran Sulfate Sodium-Induced Ulcerative Colitis on the Disposition of Tofacitinib in Rats
Sung Hun Bae, Hyo Sung Kim, Hyeon Gyeom Choi, Sun-Young Chang and So Hee Kim
Biomolecules & Therapeutics 2022; 30(6): 510-519  
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AT9283, 1-Cyclopropyl-3-(3-(5-(Morpholinomethyl)-1H-Benzo[d]Imidazole-2-yl)-1H-Pyrazol-4-yl) Urea, Inhibits Syk to Suppress Mast Cell-Mediated Allergic Response
Su Jeong Kim, Min Yeong Choi, Keun Young Min, Min Geun Jo, Jie Min Kim, Hyung Sik Kim and Young Mi Kim
Biomolecules & Therapeutics 2022; 30(6): 520-528  
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A Novel Therapeutic Effect of a New Variant of CTLA4-Ig with Four Antennas That Are Terminally Capped with Sialic Acid in the CTLA4 Region
Yongwei Piao, So Yoon Yun, Hee Soo Kim, Bo Kyung Park, Hae Chan Ha, Zhicheng Fu, Ji Min Jang, Moon Jung Back, In Chul Shin, Jong Hoon Won and Dae Kyong Kim
Biomolecules & Therapeutics 2022; 30(6): 529-539  
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Betulin, an Anti-Inflammatory Triterpenoid Compound, Regulates MUC5AC Mucin Gene Expression through NF-kB Signaling in Human Airway Epithelial Cells
Rajib Hossain, Kyung-il Kim, Fengri Jin, Hyun Jae Lee and Choong Jae Lee
Biomolecules & Therapeutics 2022; 30(6): 540-545  
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Immune Responses to Plant-Derived Recombinant Colorectal Cancer Glycoprotein EpCAM-FcK Fusion Protein in Mice
Chae-Yeon Lim, Deuk-Su Kim, Yangjoo Kang, Ye-Rin Lee, Kibum Kim, Do Sun Kim, Moon-Soo Kim and Kisung Ko
Biomolecules & Therapeutics 2022; 30(6): 546-552  
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Growth Inhibitory and Pro-Apoptotic Effects of Hirsuteine in Chronic Myeloid Leukemia Cells through Targeting Sphingosine Kinase 1
Shan Gao, Tingting Guo, Shuyu Luo, Yan Zhang, Zehao Ren, Xiaona Lang, Gaoyong Hu, Duo Zuo, Wenqing Jia, Dexin Kong, Haiyang Yu and Yuling Qiu
Biomolecules & Therapeutics 2022; 30(6): 553-561  
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Clinical Factors Affecting the Serum Retention of a Teratogenic Etretinate after the Acitretin Administration
Jong Heon Jeong, Gyu Hwan Hyun, Yu Jeong Park, Sung Won Kwon and Ai-Young Lee
Biomolecules & Therapeutics 2022; 30(6): 562-569  
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Protective Role of Corticosterone against Hydrogen Peroxide-Induced Neuronal Cell Death in SH-SY5Y Cells
Chan Lee, Jung-Hee Jang and Gyu Hwan Park
Biomolecules & Therapeutics 2022; 30(6): 570-575  
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Synthetic Homoisoflavane Derivatives of Cremastranone Suppress Growth of Colorectal Cancer Cells through Cell Cycle Arrest and Induction of Apoptosis
Ha-Eun Shin, Seul Lee, Yeram Choi, Sangkyu Park, Sangil Kwon, Jun-Kyu Choi, Seung-Yong Seo and Younghee Lee
Biomolecules & Therapeutics 2022; 30(6): 576-584  
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Hydroxyzine Induces Cell Death in Triple-Negative Breast Cancer Cells via Mitochondrial Superoxide and Modulation of Jak2/STAT3 Signaling
Rajina Shakya, Gyu Hwan Park, Sang Hoon Joo, Jung-Hyun Shim and Joon-Seok Choi
Biomolecules & Therapeutics 2022; 30(6): 585-592  
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HPV-18 E7 Interacts with Elk-1 Leading to Elevation of the Transcriptional Activity of Elk-1 in Cervical Cancer
Sung-Ho Go, Seung Bae Rho, Dong-Wha Yang, Boh-Ram Kim, Chang Hoon Lee and Seung-Hoon Lee
Biomolecules & Therapeutics 2022; 30(6): 593-602  
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Comparing Non-Communicable Disease Risk Factors in Asian Migrants and Native Koreans among the Asian Population
Heng Piao, Jae Moon Yun, Aesun Shin, Belong Cho and Daehee Kang
Biomolecules & Therapeutics 2022; 30(6): 603-615  
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Modulation of Autophagy is a Potential Strategy for Enhancing the Anti-Tumor Effect of Mebendazole in Glioblastoma Cells
Seong Bin Jo, So Jung Sung, Hong Seok Choi, Jae-Sung Park, Yong-Kil Hong and Young Ae Joe
Biomolecules & Therapeutics 2022; 30(6): 616-624  
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Chronicles of EGFR Tyrosine Kinase Inhibitors: Targeting EGFR C797S Containing Triple Mutations
Krishna Babu Duggirala, Yujin Lee and Kwangho Lee
Received: March 12, 2021; Revised: April 29, 2021; Accepted: May 7, 2021
Diabetic Nephropathy – a Review of Risk Factors, Progression, Mechanism, and Dietary Management
Vijayakumar Natesan and Sung-Jin Kim
Received: November 11, 2020; Revised: January 18, 2021; Accepted: March 26, 2021
Neuronal Autophagy: Characteristic Features and Roles in Neuronal Pathophysiology
McNeil Valencia, Sung Rae Kim, Yeseul Jang and Sung Hoon Lee
Received: January 14, 2021; Revised: March 2, 2021; Accepted: March 23, 2021

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