Biomolecules & Therapeutics 2021; 29(5): 455~570
Specialized Proresolving Mediators for Therapeutic Interventions Targeting Metabolic and Inflammatory Disorders
Yong-Hyun Han, Kyeongjin Lee, Abhirup Saha, Juhyeong Han, Haena Choi, Minsoo Noh, Yun-Hee Lee and Mi-Ock Lee
Biomolecules & Therapeutics 2021; 29(5): 455-464  
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Bioactive Lipids and Their Derivatives in Biomedical Applications
Jinwon Park, Jaehyun Choi, Dae-Duk Kim, Seunghee Lee, Bongjin Lee, Yunhee Lee, Sanghee Kim, Sungwon Kwon, Minsoo Noh, Mi-Ock Lee, Quoc-Viet Le and Yu-Kyoung Oh
Biomolecules & Therapeutics 2021; 29(5): 465-482  
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Original Articles
Matrix Metalloproteinase-8 Inhibitor Ameliorates Inflammatory Responses and Behavioral Deficits in LRRK2 G2019S Parkinson’s Disease Model Mice
Taewoo Kim, Jeha Jeon, Jin-Sun Park, Yeongwon Park, Jooeui Kim, Haneul Noh, Hee-Sun Kim and Hyemyung Seo
Biomolecules & Therapeutics 2021; 29(5): 483-491  
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Suppressive Effect of CYM50358 S1P4 Antagonist on Mast Cell Degranulation and Allergic Asthma in Mice
Wi-Jin Jeon, Ki Wung Chung, Joon-Hee Lee and Dong-Soon Im
Biomolecules & Therapeutics 2021; 29(5): 492-497  
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Change in Cationic Amino Acid Transport System and Effect of Lysine Pretreatment on Inflammatory State in Amyotrophic Lateral Sclerosis Cell Model
Sana Latif and Young-Sook Kang
Biomolecules & Therapeutics 2021; 29(5): 498-505  
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Novel Anti-Angiogenic and Anti-Tumour Activities of the N-Terminal Domain of NOEY2 via Binding to VEGFR-2 in Ovarian Cancer
Seung Bae Rho, Keun Woo Lee, Seung-Hoon Lee, Hyun Jung Byun, Boh-Ram Kim and Chang Hoon Lee
Biomolecules & Therapeutics 2021; 29(5): 506-518  
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Cyclooxygenase-2 Inhibitor Parecoxib Was Disclosed as a PPAR-γ Agonist by In Silico and In Vitro Assay
Bin Xiao, Dan-dan Li, Ying Wang, Eun La Kim, Na Zhao, Shang-Wu Jin, Dong-Hao Bai, Li-Dong Sun and Jee H. Jung
Biomolecules & Therapeutics 2021; 29(5): 519-526  
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Conformational Dynamics of Sclerostin-LRP6 Complex Analyzed by HDX-MS
Yejing Jeong, Jinuk Kim, Hee-Jung Choi and Ka Young Chung
Biomolecules & Therapeutics 2021; 29(5): 527-535  
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Hyaluronic Acid Increases Anti-Inflammatory Efficacy of Rectal 5-Amino Salicylic Acid Administration in a Murine Colitis Model
Henusha D. Jhundoo, Tobias Siefen, Alfred Liang, Christoph Schmidt, John Lokhnauth, Brice Moulari, Arnaud Béduneau, Yann Pellequer, Crilles Casper Larsen and Alf Lamprecht
Biomolecules & Therapeutics 2021; 29(5): 536-544  
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ER71/ETV2 Promotes Hair Regeneration from Chemotherapeutic Drug-Induced Hair Loss by Enhancing Angiogenesis
Tae-Jin Lee, Hee-Kyoung Kang, Jeffrey C. Berry, Hong-Gu Joo, Changwon Park, Mark J. Miller and Kyunghee Choi
Biomolecules & Therapeutics 2021; 29(5): 545-550  
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Platelet-Derived Growth Factor Receptor-α Subunit Targeting Suppresses Metastasis in Advanced Thyroid Cancer In Vitro and In Vivo
Ching-Ling Lin, Ming-Lin Tsai, Yu-hsin Chen, Wei-Ni Liu, Chun-Yu Lin, Kai-Wen Hsu, Chien-Yu Huang, Yu-Jia Chang, Po-Li Wei, Shu-Huey Chen, Li-Chi Huang and Chia-Hwa Lee
Biomolecules & Therapeutics 2021; 29(5): 551-561  
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Anticancer Activity of Indeno[1,2-b]-Pyridinol Derivative as a New DNA Minor Groove Binding Catalytic Inhibitor of Topoisomerase IIα
Kyung-Hwa Jeon, Aarajana Shrestha, Hae Jin Jang, Jeong-Ahn Kim, Naeun Sheen, Minjung Seo, Eung-Seok Lee and Youngjoo Kwon
Biomolecules & Therapeutics 2021; 29(5): 562-570  
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Poncirin Inhibits Osteoclast Differentiation and Bone Loss through Down-Regulation of NFATc1 In Vitro and In Vivo
Kwang-Hoon Chun, Hyun Chul Jin, Ki Sung Kang, Tong-Shin Chang and Gwi Seo Hwang
Received: November 5, 2018; Revised: January 24, 2019; Accepted: April 3, 2019
Alternative Methods for Testing Botulinum Toxin: Current Status and Future Perspectives
Mahesh Raj Nepal and Tae Cheon Jeong
Received: November 29, 2019; Revised: February 6, 2020; Accepted: February 17, 2020
Small Molecule Inhibitors of Middle East Respiratory Syndrome Coronavirus Fusion by Targeting Cavities on Heptad Repeat Trimers
Mahmoud Kandeel, Mizuki Yamamoto, Abdulla Al-Taher, Aya Watanabe, Kentaro Oh-hashi, Byoung Kwon Park, Hyung-Joo Kwon, Jun-ichiro Inoue and Mohammed Al-Nazawi
Received: December 2, 2019; Revised: January 13, 2020; Accepted: January 23, 2020

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