Biomolecules & Therapeutics 2022; 30(1): 1~116
Invited Review
Inhibition of Cytochrome P450 Enzymes by Drugs—Molecular Basis and Practical Applications
F. Peter Guengerich*
Biomolecules & Therapeutics 2022; 30(1): 1-18  
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Chronicles of EGFR Tyrosine Kinase Inhibitors: Targeting EGFR C797S Containing Triple Mutations
Krishna Babu Duggirala, Yujin Lee and Kwangho Lee
Biomolecules & Therapeutics 2022; 30(1): 19-27  
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Original Articles
Melatonin Protects Chronic Kidney Disease Mesenchymal Stem/Stromal Cells against Accumulation of Methylglyoxal via Modulation of Hexokinase-2 Expression
Gyeongyun Go, Yeo Min Yoon, Sungtae Yoon, Gaeun Lee, Ji Ho Lim, Su-Yeon Han and Sang Hun Lee
Biomolecules & Therapeutics 2022; 30(1): 28-37  
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Lithocholic Acid Activates Mas-Related G Protein-Coupled Receptors, Contributing to Itch in Mice
Myung-Hyun Song and Won-Sik Shim
Biomolecules & Therapeutics 2022; 30(1): 38-47  
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Novel GPR43 Agonists Exert an Anti-Inflammatory Effect in a Colitis Model
Bi-Oh Park, Jong Soon Kang, Suresh Paudel, Sung Goo Park, Byoung Chul Park, Sang-Bae Han, Young-Shin Kwak, Jeong-Hoon Kim and Sunhong Kim
Biomolecules & Therapeutics 2022; 30(1): 48-54  
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Oleanolic Acid Provides Neuroprotection against Ischemic Stroke through the Inhibition of Microglial Activation and NLRP3 Inflammasome Activation
Arjun Sapkota and Ji Woong Choi*
Biomolecules & Therapeutics 2022; 30(1): 55-63  
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Vinyl-Stilbene Inhibits Human Norovirus RNA Replication by Activating Heat-Shock Factor-1
Ahrim Lee, Jieun Sung, Dipesh S. Harmalkar, Hyeseul Kang, Hwayoung Lee, Kyeong Lee and Choongho Lee
Biomolecules & Therapeutics 2022; 30(1): 64-71  
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Licochalcone H Induces Cell Cycle Arrest and Apoptosis in Human Skin Cancer Cells by Modulating JAK2/STAT3 Signaling
Kyung-Ho Park, Sang Hoon Joo, Ji-Hye Seo, Jumi Kim, Goo Yoon, Young-Joo Jeon, Mee-Hyun Lee, Jung-Il Chae, Woo-Keun Kim and Jung-Hyun Shim
Biomolecules & Therapeutics 2022; 30(1): 72-79  
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Enhancement of Radiosensitivity by DNA Hypomethylating Drugs through Apoptosis and Autophagy in Human Sarcoma Cells
Moon-Taek Park, Sung-Dae Kim, Yu Kyeong Han, Jin Won Hyun, Hae-June Lee and Joo Mi Yi*
Biomolecules & Therapeutics 2022; 30(1): 80-89  
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Botulinum Toxin A Ameliorates Neuroinflammation in the MPTP and 6-OHDA-Induced Parkinson’s Disease Models
Hyeon Joo Ham, In Jun Yeo, Seong Hee Jeon, Jun Hyung Lim, Sung Sik Yoo, Dong Ju Son, Sung-Su Jang, Haksup Lee, Seung-Jin Shin, Sang Bae Han, Jae Suk Yun and Jin Tae Hong
Biomolecules & Therapeutics 2022; 30(1): 90-97  
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Discovery of Cellular RhoA Functions by the Integrated Application of Gene Set Enrichment Analysis
Kwang-Hoon Chun*
Biomolecules & Therapeutics 2022; 30(1): 98-116  
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Poncirin Inhibits Osteoclast Differentiation and Bone Loss through Down-Regulation of NFATc1 In Vitro and In Vivo
Kwang-Hoon Chun, Hyun Chul Jin, Ki Sung Kang, Tong-Shin Chang and Gwi Seo Hwang
Received: November 5, 2018; Revised: January 24, 2019; Accepted: April 3, 2019
Alternative Methods for Testing Botulinum Toxin: Current Status and Future Perspectives
Mahesh Raj Nepal and Tae Cheon Jeong
Received: November 29, 2019; Revised: February 6, 2020; Accepted: February 17, 2020
Small Molecule Inhibitors of Middle East Respiratory Syndrome Coronavirus Fusion by Targeting Cavities on Heptad Repeat Trimers
Mahmoud Kandeel, Mizuki Yamamoto, Abdulla Al-Taher, Aya Watanabe, Kentaro Oh-hashi, Byoung Kwon Park, Hyung-Joo Kwon, Jun-ichiro Inoue and Mohammed Al-Nazawi
Received: December 2, 2019; Revised: January 13, 2020; Accepted: January 23, 2020

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