5-Hydroxytryptophan Reduces Levodopa-Induced Dyskinesia via Regulating AKT/mTOR/S6K and CREB/ΔFosB Signals in a Mouse Model of Parkinson’s Disease
Yujin Choi1, Eugene Huh2,ψ, Seungmin Lee1, Jin Hee Kim1, Myoung Gyu Park3, Seung-Yong Seo4, Sun Yeou Kim4 and Myung Sook Oh1,2,*
1Department of Biomedical and Pharmaceutical Sciences, Graduate School, Kyung Hee University, Seoul 02447,
2Department of Oriental Pharmaceutical Science, College of Pharmacy, Kyung Hee University, Seoul 02447,
3MetaCen therapeutics Inc. R&D Center, Suwon 16229,
4College of Pharmacy, Gachon University, Incheon 21936, Republic of Korea
*E-mail: msohok@khu.ac.kr
Tel: +82-2-961-9436, Fax: +82-2-963-9436
ψPresent Address
Department of Formulae Pharmacology, College of Korean Medicine, Gachon University, Seongnam 13120, Republic of Korea
Received: November 8, 2022; Revised: January 17, 2023; Accepted: February 10, 2023; Published online: March 15, 2023.
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