Virtual Screening and Testing of GSK-3 Inhibitors Using Human SH-SY5Y Cells Expressing Tau Folding Reporter and Mouse Hippocampal Primary Culture under Tau Cytotoxicity
Chih-Hsin Lin1,†, Yu-Shao Hsieh2,†, Ying-Chieh Sun2,†, Wun-Han Huang1, Shu-Ling Chen1, Zheng-Kui Weng1, Te-Hsien Lin1, Yih-Ru Wu3, Kuo-Hsuan Chang3, Hei-Jen Huang4, Guan-Chiun Lee1,*, Hsiu Mei Hsieh-Li1,* and Guey-Jen Lee-Chen1,*
1School of Life Science, National Taiwan Normal University, Taipei 11677,
2Department of Chemistry, National Taiwan Normal University, Taipei 11677,
3Department of Neurology, Chang Gung Memorial Hospital, Taoyuan 33378,
4Department of Nursing, Mackay Junior College of Medicine, Nursing and Management, Taipei 11260, Taiwan
*E-mail:
gclee@ntnu.edu.tw (Lee GC),
hmhsieh@ntnu.edu.tw (Hsieh-Li HM),
t43019@ntnu.edu.tw (Lee-Chen GJ)
Tel: +886-2-7749-6351 (Lee GC), +886-2-7749-6354 (Hsieh-Li HM), +886-2-7749-6359 (Lee-Chen GJ)
Fax: +886-2-2931-2904 (Lee GC), +886-2-2931-2904 (Hsieh-Li HM), +886-2-2931-2904 (Lee-Chen GJ)
†The first three authors contributed equally to this work.