Biomolecules & Therapeutics : eISSN 2005-4483 / pISSN 1976-9148

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Fig. 2. PA induces G0/G1 phase arrest in MCF-7 cells. (A) MCF-7 cells were treated with the indicated concentrations of PA (10, 15 and 20 μM) for 24 h. Cells were permeabilized by ethanol and stained with PI. Cell cycle progression was assessed by flow cytometry. Representative figures of the cell cycle distribution (G0–G1, S, and G2-M) show accumulation of PA-treated cells in G0/G1phase. MCF-7 cells were arrested in G0/G1 phase 24 h after PA treatment. (B) The average percentage of the cell cycle phases is represented. The results are from 3 independent experiments and are presented as the means ± SD. Treated groups compared with the untreated control, *p<0.05.
Biomolecules & Therapeutics 2018;26:328~334
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