Fig. 3. The toxicity and anti-viral activity. (A) Anti-viral activity. Cardiomyocytes were infected with CVB3 for 1 h, and incubated with compound 1–5 or cinnamaldehyde (0.01–1000 μM). After 72 h, viral titers were determined using TCID50 assay. (B) Cytotoxicity of compound 1–5 and cinnamaldehyde (Cin) on cardiomyocytes. Cardiomyocytes were treated with 0.01–1000 μM compound 1–5 or cinnamaldehyde for 72 h. Cell proliferation was analyzed by MTT assay. Values are expressed as mean ± SD.
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