Biomolecules & Therapeutics : eISSN 2005-4483 / pISSN 1976-9148

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Fig. 1. Rhomboid protein iRhoms regulate the RGFR ligands in the ER. iRhoms binds to various EGFR ligands in the ER and facilitate their forward trafficking or ERAD pathway. The mechanism with which the fate determination of the EGFR ligands is not clear yet.
Biomolecules & Therapeutics 2016;24:109~114 https://doi.org/10.4062/biomolther.2015.149
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