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Fig. 2. Atractylodes lancea alleviates glucose intolerance. (A) Fasting serum glucose levels (mg/dL) after a 16 h fast at the end of the study. (B) Fasting serum insulin levels (ng/mL). (C) Homeostatic model assessment of insulin resistance (HOMA-IR) calculated using the formula: [Fasting insulin (μU/mL)×Fasting glucose (mg/dL)]÷405. (D) Glucose tolerance test (GTT) was performed 2 weeks after the administration of Atractylodes lancea. (E) The area under the curve (AUC) of GTT. Data are presented as mean ± SEM (n=7-10). Statistical analysis was performed using one-way ANOVA with Tukey’s post-hoc test. (A-C, E) **p<0.01, ***p<0.001: compared with ND+Veh; #p<0.05, ##p<0.01, ###p<0.001: compared with HFD+Veh. (D) *p<0.05, **p<0.01: ND+Veh vs. HFD+Veh; ##p<0.01: HFD+Veh vs. HFD+AL 30 mg/kg; +p<0.05: HFD+Veh vs HFD+AL 60 mg/kg; $p<0.05: HFD+Veh vs HFD+AL 120 mg/kg.
Biomolecules & Therapeutics 2024;32:778~792 https://doi.org/10.4062/biomolther.2024.083
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