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Fig. 6. Changes in lung tissue metabolome in OVA-induced asthma mice administered with BS012 at 100, 200 mg/kg, and dexamethasone 1.5 mg/kg. The partial least squares discriminant analysis (PLS-DA) score plot derived from (A) positive and (B) negative ionization mode. (C) Heatmap summarizing the relative levels of metabolites significantly changed in the OVA-induced group compared to the control group or BS012 treated group compared to the OVA-induced group. Relative levels represent the standardized intensity values by auto scaling (the value divided by the mean center and the standard deviation of each variable).
Biomolecules & Therapeutics 2024;32:744~758 https://doi.org/10.4062/biomolther.2024.058
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