Fig. 4. Effect of BS012 on regulating (A-C) Bcl-2 family related apoptosis proteins and (D-F) cytochrome c-initiated caspase activation pathway in ovalbumin-induced asthma mice lung tissues. Expression levels of (A) P-Bad/Bad, (B) Bax, and (C) Bcl-xl, (D) cytochrome C, (E) cleaved-caspase 9/caspase-9, and (F) cleaved-caspase 3/caspase-3 proteins in mice lung tissues were detected by western blot analysis. Quantified protein expression levels were performed by densitometric analysis. Data are presented as mean ± SEM (n=5 per group). **, *** Significantly different (p<0.01, 0.001) from Control group. #, ##, ### Significantly different (p<0.05, 0.01, 0.001) from ovalbumin group.
© Biomolecules & Therapeutics
