Fig. 1. Effect of β-Lap on pentobarbital-induced sleep in mice. The changes in (A) sleep onset latency and (B) total sleep time. β-Lap (0.1, 0.3, and 1 mg/kg, p.o.) or DZP (1 mg/kg, p.o.) was administered to mice 30 min before pentobarbital injection (45 mg/kg, i.p.). Data are expressed as mean ± SEM (n=6-10). *p<0.05 vs CTL; **p<0.01 vs CTL. CTL, Control; β-Lap, β-lapachone; DZP, Diazepam; p.o., Per oral; i.p., Intraperitoneal.
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