Fig. 5. NSC-622608 inhibits the proliferation of CML cells and induces apoptosis. (A) CCK-8 assay results showing the inhibitory effect of NSC-622608 (0, 10, 20, 50 and 100 μM) on the proliferation of KBM5 and KBM5-T315I cells. (B, C) Flow cytometry results showing that NSC-622608 could induce significant apoptosis in CML cells, especially K562-R cells.
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