Fig. 7. Effect of NAC on domperidone-induced ROS generation and cell death in HCT116 cells. HCT116 cells were treated with the ROS scavenger NAC (5 mM) for 1 h, before preincubation with domperidone (50 μM) for 48 h. (A) DCF-DA fluorescence microscopic images. (B) Graph of DCF-DA fluorescence intensity. Data are shown as the mean ± standard deviation (SD), (n=3). (C) Cell viability was measured by the MTS cell viability assay. Data are shown as the mean ± standard deviation (SD), (n=3). *p<0.05.
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