Fig. 3. Effect of salmon nasal cartilage proteoglycan (SPG) on protein expression of keratinized, moisturized factors, and MAPKs pathway in UVB-irradiated HaCaT cells. (A) Western blot analysis to measure the expression of keratinized (profilaggrin/filaggrin, involucrin, and AQP3) and moisturized (AQP3 and HAS1) factors in UVB-irradiated HaCaT cells. (B) Western blot was used to measure the expression levels of p-ERK/ERK, p-JNK/JNK, and p-p38/p38 in UVB-irradiated HaCaT cells. All protein levels were normalized to those of GAPDH. The values are presented as mean ± SEM (n=3-4). **p<0.01 and ***p<0.001 vs. Ctrl, #p<0.05, ##p<0.01, and ###p<0.001 vs. NC.
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