Biomolecules & Therapeutics : eISSN 2005-4483 / pISSN 1976-9148

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Fig. 3. Pinitol improved UVA-induced down-regulation of collagen in human skin equivalents (HSEs). Each HSEs was treated with pinitol, ultraviolet A, or pinitol after ultraviolet A irradiation. (A) Each sample was stained with hematoxylin (red) and eosin (blue) (H&E), Masson’s trichrome, and immunohistochemically stained against MMP1 or collagen I, and then examined by light microscopy. (B) Ultrastructural analysis using reconstructed HSEs has revealed the effect of pinitol on dermal collagen. The bottom four panels show structural details of the boxed areas. Scale bars, 1 μm.
Biomolecules & Therapeutics 2024;32:224~230
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