Fig. 6. Downregulation of the dopamine D2-like receptor by domperidone. (A) TNBC BT-549 and CAL-51 cells were treated with domperidone (0, 10, 20, and 50 µM) for 24 h. The immunoblot analysis of dopamine receptors DRD1 through DRD5. β-Actin was used as the loading control. (B) The fold of induction in the mRNA level analyzed by reverse transcription polymerase chain reaction. Black bars: control (0 µM domperidone). Grey bars: domperidone treatment (50 µM) for 24 h. **p<0.01 compared to the non-treated control. ND, not detected.
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