Fig. 4. LCH inhibits the expression of active form p-EGFR and p-AKT kinases. (A) Cells were treated with LCH at the indicated concentration for 48 h, then the protein levels were determined by Western blotting against phospho (p)-EGFR (Tyr1068), EGFR, p-AKT (Ser473), AKT antibodies. Actin was used as an internal control for equal loading. (B, C) Quantitation of active form p-EGFR and p-AKT compared to each total form. **p<0.01 and ***p<0.001 compared with the control.
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