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Fig. 4. Schematic view of melanocyte death induced by AQP3-downregulated keratinocytes in vitiligo under oxidative stress. AQP3 downregulation in vitiligo keratinocytes impairs cellular antioxidant responses and H2O2 uptake under oxidative stress, increasing ROS concentrations in the surrounding environment, leading to neighboring melanocyte death.
Biomolecules & Therapeutics 2023;31:648~654 https://doi.org/10.4062/biomolther.2023.112
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