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Table. 5.

Effect of prunetin on the changes in the activities of enzymatic antioxidant Vitamin C, Vitamin E and GSH kidney tissue control and experimental rats

Groups Vitamin C Vitamin E GSH
Control 1.18 ± 0.89 1.05 ± 0.04 24.69 ± 2.70
STZ (diabetic control) 0.56 ± 0.43* 0.35 ± 0.008* 12.64 ± 1.24*
PRU 80 mg/kg 1.18 ± 0.09 1.06 ± 0.04 24.88 ± 1.93
STZ+PRU 20 mg/kg 0.68 ± 0.51# 0.40 ± 0.01# 16.81 ± 0.60#
STZ+PRU 40 mg/kg 0.94 ± 0.72# 0.49 ± 0.26# 20.82 ± 1.01#
STZ+PRU 80 mg/kg 1.16 ± 0.85## 1.04 ± 0.04## 23.13 ± 0.73##

Values are expressed as means ± SD (n=6 rats for each group; test were performed in triplicate). *p<0.05 versus Control group; #p<0.05, ##p<0.01 versus STZ (diabetic control group).

Biomolecules & Therapeutics 2023;31:619~628 https://doi.org/10.4062/biomolther.2023.068
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