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Table. 4.

Effect of prunetin on the changes in the activities of enzymatic antioxidant SOD, CAT and GPx kidney tissue control and experimental rats

Groups SOD CAT GPx
Control 19.67 ± 1.86 37.40 ± 1.12 7.89 ± 0.50
STZ (diabetic control) 7.61 ± 1.05* 20.45 ± 1.30* 3.17 ± 0.28*
PRU 80 mg/kg 19.46 ± 1.74 37.20 ± 0.98 7.98 ± 0.51
STZ+PRU 20 mg/kg 10.20 ± 0.51# 25.48 ± 0.34# 4.70 ± 0.41#
STZ+PRU 40 mg/kg 13.28 ± 0.33# 29.34 ± 0.45# 6.12 ± 0.17#
STZ+PRU 80 mg/kg 18.48 ± 0.86## 36.69 ± 1.46## 7.54 ± 0.28##

Values are expressed as means ± SD (n=6 rats for each group; test were performed in triplicate). *p<0.05 versus Control group; #p<0.05, ##p<0.01 versus STZ (diabetic control group).

Biomolecules & Therapeutics 2023;31:619~628 https://doi.org/10.4062/biomolther.2023.068
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