
Effect of prunetin on hexokinase in the tissues of control and experimental rats
Hexokinase (µmol of glucose phosphorylated/min/g protein) | |||
---|---|---|---|
Groups | Liver | Kidney | Skeletal muscle |
Control | 152.34 ± 11.60 | 143.78 ± 10.95 | 172.16 ± 13.11 |
STZ (diabetic control) | 94.84 ± 7.26 |
78.35 ± 6.00 |
104.43 ± 7.99 |
PRU (80 mg/kg b.w.) | 154.20 ± 11.74 | 145.41 ± 11.07 | 173.14 ± 13.18 |
STZ+PRU (20 mg/kg b.w.) | 103.06 ± 7.89 |
89.71 ± 6.87 |
121.52 ± 9.30 |
STZ+PRU (40 mg/kg b.w.) | 118.33 ± 9.01 |
114.77 ± 8.74 |
139.10 ± 10.59 |
STZ+PRU (80 mg/kg b.w.) | 149.71 ± 11.46 |
139.58 ± 10.68 |
165.87 ± 12.70 |
Values are expressed as means ± SD (n=6 rats for each group; test were performed in triplicate). *p<0.05 versus Control group; #p<0.05, ##p<0.01 versus STZ (diabetic control group).