Fig. 3. Anticancer effect of resveratrol in CRC cells. (A) Inhibition of cell viability by resveratrol (Res). Res, G1, and G15 were treated in RKO and WiDr cells for 48 h, while cell viability was measured by MTT assay as described in the Materials and Methods. Data represent the mean ± SD (n=6). *p<0.05; ***p<0.001 (vs. control, one-way ANOVA with Dunnett’s post hoc test). (B) Suppression of cell proliferation by Res. As the clonogenic assay, the survival fraction (SF) was calculated. Data represent the mean ± SD (n=3). *p<0.05; **p<0.001; ***p<0.0001 (One-way ANOVA with Dunnett’s post hoc test). (C) Change in protein expression levels by Res. Cells were treated with Res (100 μM) and G1 (2 μM) for 3 h. All data represent the mean ± SD (n=3). *p<0.05, **p<0.0001 (Two-way ANOVA with Sidak’s post hoc test).
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