Fig. 7. Effect of rhHAPLN1 on migration and tube-forming in HUVECs. (A) Representative images of tube-forming capacity of senescent HUVECs were treated with rhHAPLN1. Quantification of the number of meshes, branching intervals and total tube length. (B, C) The wound pictures were captured by light microscope at 0 and 8 h, after which wound area was determined using ImageJ. Scale bar=100 μm. #p<0.05 versus Control (young HUVECs). *p<0.05; **p<0.005; and ***p<0.0005 versus IL-17A treatment or Control (senescent HUVECs, n=3 per group).
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