Fig. 5. Effect of sinapic acid (SA) on mitochondrial fission and fusion in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-treated mice. (A-E) The expression of mitochondrial fission-related proteins, including Drp1, phospho-Drp1 Ser616, and phospho-Drp1 Ser637, and mitochondrial fusion-related proteins, including mitofusin 2 (MFN2) and OPA1, was measured by western blot after treatment with both MPTP and SA (n=6). Full-length blots are shown in the supplementary information. The results are presented as the mean ± SEM. *p<0.05 compared to the control group, #p<0.05 compared to the MPTP group.
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