Fig. 2. Effect of sinapic acid (SA) on N-methyl-4-phenylpyridinium (MPP+)-treated SH-SY5Y cells exposed to the REV-ERB α antagonist SR8278 and the REV-ERB α agonist GSK4112. (A) The protein expression of REV-ERB was measured by western blot after treatment with both MPP+ and SA (n=5). (B, C) The protein expression of tyrosine hydroxylase (TH) and REV-ERB α was measured by western blot after treatment with MPP+, SA, SR and GSK (n=5). Full-length blots are shown in the supplementary information. The results are presented as the mean ± SEM. *p<0.05 compared to the control group, #p<0.05 compared to the MPP+ group, $p<0.05 compared to the SA group.
© Biomolecules & Therapeutics
