Biomolecules & Therapeutics : eISSN 2005-4483 / pISSN 1976-9148

Download original image
Fig. 1. Effect of sinapic acid (SA) on N-methyl-4-phenylpyridinium (MPP+)-treated SH-SY5Y cells. (A) Effect of SA on the viability of SH-S5Y5 cells (n=5). (B) Evaluation of the dose-dependent effects of SA on MPP+-treated cells (n=5). (C) The protein expression of tyrosine hydroxylase (TH) was measured by western blot after treatment with both MPP+ and SA (n=5). (D) The cellular ATP content and (E) median glutamate dehydrogenase (GDH) activity were measured using a commercially available assay kit to examine mitochondrial function (n=5). Full-length blots are shown in the supplementary information. The results are presented as the mean ± SEM. *p<0.05 compared to the control group, #p<0.05 compared to the MPP+ group.
Biomolecules & Therapeutics 2022;30:409~417
© Biomolecules & Therapeutics