Table 1 Adiponectin receptors
| Receptor | Affinity toward adiponectin | Expression site | Feature |
|---|---|---|---|
| AdipoR1 | High affinity toward globular adiponectin | Ubiquitous | Integral membrane protein |
| Can bind to full-length adiponectin | Especially skeletal muscle and liver | ||
| AdipoR2 | Intermediate affinity toward both globular adiponectin and full-length adiponectin | Restricted to liver | Integral membrane protein |
| T-cadherin | Binds to the MMW and HMW forms of adiponectin | Endothelial cell | Interacts with eukaryotic post-translational modified adiponectin |
| Smooth muscle cell | |||
| Attached to the plasma membrane by glycosyl phosphatidylinositol anchor | Does not interact with globular or bacterial-produced adiponectin |