Biomolecules & Therapeutics : eISSN 2005-4483 / pISSN 1976-9148

Table. 2.

Biomedical activity and application of glycerolipids

Subclass Name Activity Medical application Ref.
Monoacylglycerol Monocaprylate Formation of transient or permanent pores in the membrane Antimicrobial Hyldgaard et al., 2012
MonolaurinMoncaprin Bactericidal activity against H. pylori Infectious disease Bergsson et al., 2002
Monoolein Antimicrobial activity against S. aureus and E. coli Antimicrobial Jumina et al., 2019
MAG-DHA Downregulation of NF-kB and upregulation of PTEN Non-small cell lung cancer Morin and Fortin, 2017
Diacylglycerol Monogalactosyl diacylglycerol Inhibition of CD31 positive tumor blood vessel growth. Colon cancer Maeda et al., 2013
1,3-Diacylglycerol Increasing oxidation of fatty acid and suppressing chylomicron formation Obesity and insulin resistance Saito et al., 2007
Triacylglycerol Medium-chain triglyceride Suppression of IL-6, iNOS, cyclooxygenase-2 and IL-10 and activation of NF-kB and p38 MAPK pathways Insulin resistance Geng et al., 2016
Medium-chain triglyceride Metabolized to ketone bodies to the brain Neurological and metabolic disorders Augustin et al., 2018b
Tricaprilin (AC-1202) Reducing oxidative damage and improvement of respiration rate in brain Alzheimer’s disease Henderson et al., 2009
Biomolecules & Therapeutics 2021;29:465~482 https://doi.org/10.4062/biomolther.2021.107
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