Fig. 6. Effect of luteolin on the expression and production of IL-10, VEGF, MMP-2, and MMP-9 in macrophages stimulated by conditioned medium from human endometriotic 12Z cells. THP-1 macrophages were stimulated with conditioned medium from 12Z cells for 24 h. The activated macrophages (EAMs) were treated with luteolin (15, 30, and 60 μM) for 24 h. Real-time RT-PCR was performed to measure the mRNA levels of IL-10, VEGF, MMP-2, and MMP-9 in macrophages. GAPDH was used as an internal control. #p<0.05 as compared with macrophage control, and *p<0.05 as compared with EAMs control.
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