Biomolecules & Therapeutics : eISSN 2005-4483 / pISSN 1976-9148

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Fig. 3. Effect of Tat-Trx1 protein against H2O2-induced cellular signaling pathways in HT-22 cells. One-hour pretreatment of HT-22 cells with Tat-Trx1 protein (5 μM) or Trx1 protein was followed by treatment with H2O2 (700 μM). Then, the expression levels of (A) ASK1, (B) MAPK, (C) Akt, (D) p65 and (E) Bcl-2, Bax, Caspase-3 and cleaved Caspase-3 were determined by Western blotting. Band intensity was measured by densitometer. The bars in the figure represent the mean ± SEM obtained from 3 independent experiments. *p<0.05 compared with H2O2-treated cells.
Biomolecules & Therapeutics 2021;29:321~330
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