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Fig. 4. CYM50358 protects against mucin production. (A) Panels show PAS/hematoxylin-stained sections of lung tissues from the PBS group, OVA group, and CYM50358-treated OVA groups (before sensitization or before challenge). In PAS staining, mucin is stained as purple color. Darker and thicker purple color is observed surrounding the bronchiole in the OVA group compared to the PBS group. (B) Mucous production was measured by counting the number of PAS-positive cells (red arrows) per mm of bronchiole (n=5 per group). ***p<0.001 vs. the PBS-treated group, ###p<0.001 vs. the OVA-treated group.
Biomolecules & Therapeutics 2021;29:492~497 https://doi.org/10.4062/biomolther.2020.206
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