Fig. 5. The expression levels of post-synaptic density protein 95 (PSD95) in 5XFAD mice. Western blot analysis was conducted 12 weeks after the Theracurmin administration. The expression levels of PSD95 were measured in the cortex (A) and the hippocampus (B). The last administration of Theracurmin (100, 300 or 1,000 mg/kg) or vehicle solution was performed 1 h before sacrifice. The decreased expression levels of PSD95 were reversed by Theracurmin administration. Immunoreactivity was normalized to the controls is presented as mean ± SEM (n=5–6/group). *p<0.05 when compared to the control group; #p<0.05 when compared to the vehicle-treated group.
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