Biomol Ther 2019; 27(5): 423~501
Traditional and Novel Mechanisms of Heat Shock Protein 90 (HSP90) Inhibition in Cancer Chemotherapy Including HSP90 Cleavage
Sangkyu Park, Jeong-A Park, Jae-Hyung Jeon and Younghee Lee
Biomol Ther 2019; 27(5): 423-434  
PDF PubMed Central
Original Articles
Combination of a Rapidly Penetrating Agonist and a Slowly Penetrating Antagonist Affords Agonist Action of Limited Duration at the Cellular Level
Larry V. Pearce, Jihyae Ann, Peter M. Blumberg and Jeewoo Lee
Biomol Ther 2019; 27(5): 435-441  
PDF PubMed Central
Asiatic Acid Protects Dopaminergic Neurons from Neuroinflammation by Suppressing Mitochondrial ROS Production
Dong Chen, Xiao-Ya Zhang, Jing Sun, Qi-Jie Cong, Wei-Xiong Chen, Hafiz Muhammad Ahsan, Jing Gao and Jin-Jun Qian
Biomol Ther 2019; 27(5): 442-449  
PDF PubMed Central
Anxiolytic Action of Taurine via Intranasal Administration in Mice
Jung Hwa Jung and Sung-Jin Kim
Biomol Ther 2019; 27(5): 450-456  
PDF PubMed Central
Enrichment of Short-Chain Ceramides and Free Fatty Acids in the Skin Epidermis, Liver, and Kidneys of db/db Mice, a Type 2 Diabetes Mellitus Model
Minjeong Kim, Haengdueng Jeong, Buhyun Lee, Yejin Cho, Won Kee Yoon, Ahreum Cho, Guideock Kwon, Ki Taek Nam, Hunjoo Ha and Kyung-Min Lim
Biomol Ther 2019; 27(5): 457-465  
PDF PubMed Central
Decursinol Angelate Ameliorates Dextran Sodium Sulfate-Induced Colitis by Modulating Type 17 Helper T Cell Responses
Bikash Thapa, Seongwon Pak, Hyun-Joo Kwon and Keunwook Lee
Biomol Ther 2019; 27(5): 466-473  
PDF PubMed Central Supplementary File
Arg-Leu-Tyr-Glu Suppresses Retinal Endothelial Permeability and Choroidal Neovascularization by Inhibiting the VEGF Receptor 2 Signaling Pathway
Wonjin Park, Yi-Yong Baek, Joohwan Kim, Dong Hyun Jo, Seunghwan Choi, Jin Hyoung Kim, Taesam Kim, Suji Kim, Minsik Park, Ji Yoon Kim, Moo-Ho Won, Kwon-Soo Ha, Jeong Hun Kim, Young-Guen Kwon and Young-Myeong Kim
Biomol Ther 2019; 27(5): 474-483  
PDF PubMed Central Supplementary File
Curcumin-Induced Autophagy Augments Its Antitumor Effect against A172 Human Glioblastoma Cells
Jong-Eun Lee, Sung Sik Yoon and Eun-Yi Moon
Biomol Ther 2019; 27(5): 484-491  
PDF PubMed Central
Novel Isoquinolinamine and Isoindoloquinazolinone Compounds Exhibit Antiproliferative Activity in Acute Lymphoblastic Leukemia Cells
Catrin Roolf, Jan-Niklas Saleweski, Arno Stein, Anna Richter, Claudia Maletzki, Anett Sekora, Hugo Murua Escobar, Xiao-Feng Wu, Matthias Beller and Christian Junghanss
Biomol Ther 2019; 27(5): 492-501  
PDF PubMed Central Supplementary File


Effects and Mechanisms of Taurine as a Therapeutic Agent
Stephen Schaffer, and Ha Won Kim
Received: December 18, 2017; Revised: January 29, 2018; Accepted: January 31, 2018
The Pentose Phosphate Pathway as a Potential Target for Cancer Therapy
Eunae Sandra Cho, Yong Hoon Cha, Hyun Sil Kim, Nam Hee Kim, and Jong In Yook
Received: September 12, 2017; Revised: October 17, 2017; Accepted: October 19, 2017
Dysregulation of NRF2 in Cancer: from Molecular Mechanisms to Therapeutic Opportunities
Byung-Jin Jung, Hwan-Sic Yoo, Sooyoung Shin, Young-Joon Park, and Sang-Min Jeon
Received: September 27, 2017; Revised: October 19, 2017; Accepted: October 24, 2017

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