Biomolecules & Therapeutics : eISSN 2005-4483 / pISSN 1976-9148

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Fig. 5. Relative DNA content according to cell cycle stage. Cell cycle progression was analyzed via flow cytometry with propidium iodide (PI) staining using MCF-7 and MDA-MB-231 cells treated with 50 μM imidazole [clotrimazole (CTZ) or ketoconazole (KCZ)] or triazole [fluconazole (FCZ) or itraconazole (ICZ)] compounds for 24 h. Histograms were obtained from MCF-7 (A) and MDA-MB-231 (B) cells via flow cytometry. Bar graphs were obtained by analyzing the relative cell cycle phase distribution of MCF-7 (C) and MDA-MB-231 (D) cells. The data were analyzed using Cell Quest software (Becton-Dickinson). This experiment was performed three times and data are expressed as means ± standard deviation of triplicate determinations. *p<0.05, **p<0.01, ***p<0.001.
Biomolecules & Therapeutics 2018;26:494~502 https://doi.org/10.4062/biomolther.2018.042
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