Biomolecules & Therapeutics : eISSN 2005-4483 / pISSN 1976-9148

Download original image
Fig. 3. Effects of flavonoids on disaggregation of preformed Aβ1–42 fibrils. Preformed Aβ1–42 fibrils (20 μM) were incubated with ThT (5 μM) various concentrations of test compounds. The fluorescent intensity of ThT-Aβ fibrils were measured every 2.5 min using a plate reader. (A) Time-course of disaggregation of Aβ1–42 fibrils in the presence of various concentrations of amentoflavone. (B) Concentration-dependent disaggregating effects of the test compounds on Aβ1–42 fibrils were plotted.
Biomolecules & Therapeutics 2020;28:145~151
© Biomolecules & Therapeutics