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Fig. 7. Reduction of G0S2 expression downregulates β-catenin and upregulates E-cadherin. MDA-MB-231 cells were treated with G0S2 siRNA for 48 h. (A) The expressions of E-cadherin (left) and β-catenin (right) were observed by confocal microscopy. Scale bar indicates 20 μm. (B) Whole cell lysate was subjected to western blot analysis for E-cadherin (left) and β-catenin (right) expression. The band intensities were measured with Quantity One software. Protein levels were normalized against α-tubulin levels. The data is shown as mean ± SEM (n=3). Statistically significant differences from control when *p<0.05.
Biomolecules & Therapeutics 2019;27:591~602 https://doi.org/10.4062/biomolther.2019.063
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