Biomolecules & Therapeutics : eISSN 2005-4483 / pISSN 1976-9148

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Fig. 1. Histopathological and physiological features of skin in Rab25 KO mice. (A) Representative immunohistochemistry images for Rab25 in 5-week old WT and Rab25 KO mice. (B) mRNA expression of Rab25 was normalized to that of GAPDH. Graphs represent mean ± SEM (Unpaired student’s t-test, n=4, **p<0.01). (C) Representative hematoxylin and eosin (H&E) staining images of WT and Rab25 KO mouse skin (HF: hair follicle, SG: sebaceous gland). (D) Skin hydration and epidermal water loss were measured by close attachment of Delfin’s vapometer and moisturemeter on the dorsal skin of 9-week old mice. Graphs represent mean ± SEM (Unpaired student’s t-test, *p<0.05, **p<0.01).
Biomolecules & Therapeutics 2019;27:553~561 https://doi.org/10.4062/biomolther.2019.125
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