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Fig. 6. In vivo efficacy of poncirin on LPS-induced bone destruction. Mice (n=5) received i.p. injections of LPS or saline on day 0 and day 4. Poncirin was orally administrated every day for 8 days. The mice were sacrificed 8 days after the first injection of LPS, and the femurs were collected. The femurs were imaged with a micro-CT machine. Bone volume over total trabecular volume was quantified using VGStudio. *p<0.05 compared to the LPS group. LPS, lipopolysaccharide.
Biomol Ther 2020;28:337~343 https://doi.org/10.4062/biomolther.2018.216
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