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Fig. 6. RLYE inhibits laser-induced CNV. Mice were intravitreally injected with saline, EYLR, or RLYE 10 days after laser photocoagulation. (A, B) The eyes were enucleated from the mice sacrificed by inhalation of CO2 gas and fixed in 3.7% formaldehyde. Tissue sessions were stained with H&E. The CNV areas were quantified using ImageJ software (NIH) (n=6). Scale bar=50 μm. (C, D) Mice were perfused with FITC-dextran dissolved in saline 14 days after laser photocoagulation and observed under a fluorescence microscope. Scale bar=200 μm. The CNV areas were quantified using ImageJ software (NIH) (n=6). **p<0.01.
Biomol Ther 2019;27:474~483 https://doi.org/10.4062/biomolther.2019.041
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