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Fig. 4. DA ameliorates DSS-induced colitis in mice. (A) Schematic diagram of experimental procedure. (B) Body weight was measured daily and represented as a mean (± SEM) percentage of body weight. (C) Disease activity index (DAI) was scored as describe in “Materials and Methods”. Shown are the means (± SEM) of DAI 9 d after starting DSS administration. Results are obtained from two separate replicate experiments, each involving six mice. (D) At day 9, mice were euthanized, and the colons were isolated and photographed. Colon length was measured. (E) IL-6 level in the plasma at day 9 was analyzed by CBA. (F) Colon were stained with hematoxylin and eosin (H&E). Shown are the representative H&E-stained sections and means (± SD) of the histological scores. *p<0.05, **p<0.01.
Biomol Ther 2019;27:466~473
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