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Fig. 5. Expression profiles for enzymes or molecules related to lipid metabolism. The mRNA expression levels in the (A) skin and (B) liver of db/m and db/db mice were determined using real-time PCR. The analyzed genes were LXRα (liver X receptor α, NR1H3), LXRβ (liver X receptor β, NR1H2), PPARγ (peroxisome proliferator activated receptor gamma), Elovl6 (elongation of long chain fatty acids 6), Elovl1 (elongation of long chain fatty acids 1), Elovl4 (elongation of long chain fatty acids 4), FAS (fatty acid synthase), and SCD (stearoyl-CoA desaturase). Values were normalized to glyceraldehyde 3-phosphate dehydrogenase (GAPDH) level. Data are presented as the mean ± SE (n=3, *p<0.05 and **p<0.01).
Biomol Ther 2019;27:457~465 https://doi.org/10.4062/biomolther.2018.214
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