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Fig. 2. Calcium signal following simultaneous addition of capsaicin together with an antagonist. At 90 s 300 nM capsaicin was added together with the indicated concentrations of the indicated antagonist, and intracellular calcium levels in CHO cells stably expressing rat TRPV1 were monitored as a function of time using Fura2 as a calcium reporter. The antagonists were (A) BCTC, (B) I-RTX, (C) JYL-827, (D) AMG9810, (E) Capsazepine. Results shown represent the averaged signal from 35–50 cells measured simultaneously in a single experiment and are representative of the 3 experiments performed.
Biomol Ther 2019;27:435~441 https://doi.org/10.4062/biomolther.2019.013
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