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Fig. 6. CYC116 inhibits phosphorylations of Syk and Syk-mediated downstream proteins in BMMCs. BMMCs were stimulated with 50 ng/ml antigen for 10 min with or without CYC116. The cell lysates were subjected to Western blot analysis. (A, B) Representative Western blot images (upper panels) and band densities as the mean ± SEM (lower panels) are shown from three independent experiments. Significant differences compared to antigen-only group are indicated, *p<0.05 and **p<0.01. Ag, antigen.
Biomol Ther 2019;27:311~317
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